Publications

Ruetz, M., Campanello, G.C., Purchal, M., Shen, H., McDevitt, L., Gouda, H., Wakabayashi, S., Zhu, J., Rubin, E.J., Warncke, K., Mootha, V.K., Koutmos, M., Banerjee, R. An itaconyl-CoA-derived biradical on methylmalonyl-CoA mutase inhibits propionate metabolism. Science, 2019, 366, 589-593.

Wang, L.W.*, Shen, H.*, Nobre, L.*, Ersing, I.*, Paulo, J.A., Trudeau, S., Sommermann, T., Ma, Y., Reinstadler, B., Nomburg, J., Cahir-McFarland, E., Gygi, S.P., Mootha, V.K., Weekes, M.P., Gewurz, B.E. Epstein-Barr Virus Induced One-Carbon Metabolism Drives B-Cell Transformation. Cell Metabolism,2019, Jun 25. pii: S1550-4131(19)30306-7.

Shen, H., Campanello, G.C., Flicker, D., Grabarek, Z., Hu, J., Luo, C., Banerjee, R., and Mootha, V.K. The human knockout gene CLYBL connects itaconate to vitamin B12. Cell, 2017, 171, 771-782 e711. Featured article with a Preview

Cracan, V., Titov, D.V., Shen, H., Grabarek, Z., and Mootha, V.K. A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells. Nature Chemical Biology, 2017, 13, 1088-1095.

Calvo, S.E., Julien, O., Clauser, K.R., Shen, H., Kamer, K.J., Wells, J.A., and Mootha, V.K. Comparative analysis of mitochondrial N-termini from mouse, human, and yeast. Mol Cell Proteomics, 2017, 16, 512-523.

Shen, H.,Giordano, F., Wu, Y., Chan, J., Zhu, C., Milosevic, I., Wu, X., Yao, K., Chen, B., Baumgart, T., Sieburth, D., and De Camilli, P. Coupling between endocytosis and sphingosine kinase 1 recruitment. Nature Cell Biology, 2014, 16, 652-662.

Park, R.J. *, Shen, H.*, Liu, L., Liu, X., Ferguson, S.M., and De Camilli, P. Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors. Journal of Cell Science, 2013, 126, 5305-5312. 

Shen, H., Pirruccello, M., De Camilli, P. SnapShot: Membrane curvature sensors and generators. Cell, 2012, 150, 1300

Sousa, L.P., Lax, I., Shen, H., Ferguson, S.M., De Camilli, P., and Schlessinger, J. Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane. Proc Natl Acad Sci U S A, 2012, 109, 4419-4424.

Milosevic, I., Giovedi, S., Lou, X., Raimondi, A., Collesi, C., Shen, H., Paradise, S., O’Toole, E., Ferguson, S., Cremona, O., and De Camilli, P. Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission. Neuron, 2011, 72, 587-601.

Liang, L., Shen, H., De Camilli, P., Toomre, D.K., and Duncan, J.S. An expectation maximization based method for subcellular particle tracking using multi-angle TIRF microscopy. Med Image Comput Comput Assist Interv, 2011, 14, 629-636.

Shen, H., Ferguson, S.M., Dephoure, N., Park, R., Yang, Y., Volpicelli-Daley, L., Gygi, S., Schlessinger, J., and De Camilli, P. Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin. Mol Biol Cell, 2011, 22, 493-502.

Liang, L., Shen, H., De Camilli, P., and Duncan, J.S. Tracking clathrin coated pits with a multiple hypothesis based method. Med Image Comput Comput Assist Interv, 2010, 13, 315-322.

Ferguson, S.M., Raimondi, A.*, Paradise, S.*, Shen, H.*, Mesaki, K., Ferguson, A., Destaing, O., Ko, G., Takasaki, J., Cremona, O., E, O.T., and De Camilli, P. Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits. Dev Cell, 2009, 17, 811-822.  

Complete List of Published Works on Pubmed