*co-authors; #co-corresponding authors; bold, Shen lab member

Shi X*, Reinstadler B*, Shah H, To T-L, Byrne K, Summer L, Calvo SE, Goldberger O, Doench JG, Mootha VK, Shen H. (2021) Combinatorial G x G x E CRISPR screening and functional analysis highlights SLC25A39 in mitochondrial GSH transport. bioRxiv, 2021.2009.2022.461361.

Moen JM, Mohler K, Rogulina S, Shi X, Shen H, Rinehart J. Optimization of a phosphothreonine orthogonal translation system enhances access to the Human Phosphoproteome. 2021 Submitted

Jourdain AA, Skinner OS, Kawakami A, Goodman RP, Shen H, Kemény LV, Joesch-Cohen L, Rees MG, Roth JA, Fisher DE, Mootha VK. Salvage of Ribose from Uridine or RNA Supports Glycolysis when Glucose is Limiting. bioRxiv 2021

Guillén-Samander A, Leonzino M, Hanna MG, Tang N, Shen H, De Camilli P. VPS13D bridges the ER to mitochondria and peroxisomes via Miro. J Cell Biol 2021 3;220(5): e202010004

Shen H. An IRON-clad Connection between Aging Organelles. Cell 2020 180(2):214-216 (preview)

Prior to 2020

Ruetz, M., Campanello, G.C., Purchal, M., Shen, H., McDevitt, L., Gouda, H., Wakabayashi, S., Zhu, J., Rubin, E.J., Warncke, K., Mootha, V.K., Koutmos, M., Banerjee, R. An itaconyl-CoA-derived biradical on methylmalonyl-CoA mutase inhibits propionate metabolism. Science, 2019, 366, 589-593.

Wang, L.W.*, Shen, H.*, Nobre, L.*, Ersing, I.*, Paulo, J.A., Trudeau, S., Sommermann, T., Ma, Y., Reinstadler, B., Nomburg, J., Cahir-McFarland, E., Gygi, S.P., Mootha, V.K., Weekes, M.P., Gewurz, B.E. Epstein-Barr Virus Induced One-Carbon Metabolism Drives B-Cell Transformation. Cell Metabolism,2019, Sep 3;30(3):539-555.e11. 

Shen, H., Campanello, G.C., Flicker, D., Grabarek, Z., Hu, J., Luo, C., Banerjee, R., and Mootha, V.K. The human knockout gene CLYBL connects itaconate to vitamin B12. Cell, 2017, 171, 771-782 e711. Featured article with a Preview

Cracan, V., Titov, D.V., Shen, H., Grabarek, Z., and Mootha, V.K. A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells. Nature Chemical Biology, 2017, 13, 1088-1095.

Calvo, S.E., Julien, O., Clauser, K.R., Shen, H., Kamer, K.J., Wells, J.A., and Mootha, V.K. Comparative analysis of mitochondrial N-termini from mouse, human, and yeast. Mol Cell Proteomics, 2017, 16, 512-523.

Shen, H.,Giordano, F., Wu, Y., Chan, J., Zhu, C., Milosevic, I., Wu, X., Yao, K., Chen, B., Baumgart, T., Sieburth, D., and De Camilli, P. Coupling between endocytosis and sphingosine kinase 1 recruitment. Nature Cell Biology, 2014, 16, 652-662.

Park, R.J. *, Shen, H.*, Liu, L., Liu, X., Ferguson, S.M., and De Camilli, P. Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors. Journal of Cell Science, 2013, 126, 5305-5312. 

Shen, H., Pirruccello, M., De Camilli, P. SnapShot: Membrane curvature sensors and generators. Cell, 2012, 150, 1300

Sousa, L.P., Lax, I., Shen, H., Ferguson, S.M., De Camilli, P., and Schlessinger, J. Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane. Proc Natl Acad Sci U S A, 2012, 109, 4419-4424.

Milosevic, I., Giovedi, S., Lou, X., Raimondi, A., Collesi, C., Shen, H., Paradise, S., O’Toole, E., Ferguson, S., Cremona, O., and De Camilli, P. Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission. Neuron, 2011, 72, 587-601.

Liang, L., Shen, H., De Camilli, P., Toomre, D.K., and Duncan, J.S. An expectation maximization based method for subcellular particle tracking using multi-angle TIRF microscopy. Med Image Comput Comput Assist Interv, 2011, 14, 629-636.

Shen, H., Ferguson, S.M., Dephoure, N., Park, R., Yang, Y., Volpicelli-Daley, L., Gygi, S., Schlessinger, J., and De Camilli, P. Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin. Mol Biol Cell, 2011, 22, 493-502.

Liang, L., Shen, H., De Camilli, P., and Duncan, J.S. Tracking clathrin coated pits with a multiple hypothesis based method. Med Image Comput Comput Assist Interv, 2010, 13, 315-322.

Ferguson, S.M., Raimondi, A.*, Paradise, S.*, Shen, H.*, Mesaki, K., Ferguson, A., Destaing, O., Ko, G., Takasaki, J., Cremona, O., E, O.T., and De Camilli, P. Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits. Dev Cell, 2009, 17, 811-822.  

Complete List of Published Works on Pubmed

updated 2021-09-22